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compute the melting temperature of nucleic acid duplex

This program computes, for a nucleic acid duplex, the enthalpy, the entropy and the melting temperature of the helix-coil transitions. Three types of hybridisation are possible: DNA/DNA, DNA/RNA, and RNA/RNA. The program first computes the hybridisation enthalpy and entropy from the elementary parameters of each Crick's pair by the nearest-neighbor method. Then the melting temperature is computed. The set of thermodynamic parameters can be easily changed, for instance following an experimental breakthrough.

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Arkkitehtuuri Paketin koko Koko asennettuna Tiedostot
all 3,580.2 kt5,294.0 kt [tiedostoluettelo]